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4-((1S)-1-AMINO-1-CARBOXYETHYL)BENZOIC ACID

(+)-Alpha-Methyl-4-Carboxyphenylglycine

CAS: 150145-89-4

Molecular Formula: C10H11NO4

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4-((1S)-1-AMINO-1-CARBOXYETHYL)BENZOIC ACID - Names and Identifiers

Name (+)-Alpha-Methyl-4-Carboxyphenylglycine
Synonyms (S)-MCPG
(+)-MCPG
(+)-Α-METHYL-4-CARBOXYPHENYLGLYCINE
(S)-ALFA-METHYL-4-CARBOXYPHENYLGLYCINE
(S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE
(+)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE
(+)-Alpha-Methyl-4-Carboxyphenylglycine
4-((1S)-1-AMINO-1-CARBOXYETHYL)BENZOIC ACID
(S)-alpha-Methyl-4-carboxyphenylglycine(S)-MCPG
S(+)-ALPHA-AMINO-4-CARBOXY-ALPHA-METHYL-BENZENEACETIC ACID
CAS 150145-89-4

4-((1S)-1-AMINO-1-CARBOXYETHYL)BENZOIC ACID - Physico-chemical Properties

Molecular FormulaC10H11NO4
Molar Mass209.2
Solubility 0.1 M NaOH: 15mg/mL
Appearancesolid
ColorWhite to off-white
Storage ConditionStore at RT
In vitro study (S)-MCPG (100 μM) has no detectable effects on basal spine formation or elimination mechanisms in WT slice cultures. (S)-MCPG prevents the increase in spine turnover triggered by TBS and interferes with the mechanisms of activity-dependent spine stabilization in Hippocampal slice cultures.

4-((1S)-1-AMINO-1-CARBOXYETHYL)BENZOIC ACID - Risk and Safety

Safety Description24/25 - Avoid contact with skin and eyes.
WGK Germany3
HS Code29224985

4-((1S)-1-AMINO-1-CARBOXYETHYL)BENZOIC ACID - Preparation solution concentration reference

 1mg5mg10mg
1 mM4.78 ml23.901 ml47.801 ml
5 mM0.956 ml4.78 ml9.56 ml
10 mM0.478 ml2.39 ml4.78 ml
5 mM0.096 ml0.478 ml0.956 ml
Last Update:2024-01-02 23:10:35

4-((1S)-1-AMINO-1-CARBOXYETHYL)BENZOIC ACID - Reference Information

biological activity (S)-MCPG (( )-MCPG) it is a potent class I/II metabotropic glutamate receptor (mGluRs) antagonist and is the active isomer of (RS)-MCPG (HY-100371). (S)-MCPG can be used to study the role of mGluRs in spatial learning.
Animal Model: Male Lister-Hooded rats in the learning of the Morris water maze
Dosage: 20 μg
Administration: Intraventricular injection; 20 μg; 4 days
Result: Impaired the performance of rats in the spatial version of the Morris water maze, but 1/10 of this dose did not.
Last Update:2024-04-09 20:52:54
4-((1S)-1-AMINO-1-CARBOXYETHYL)BENZOIC ACID
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SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
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Product Name: (S)-MCPG Visit Supplier Webpage Request for quotation
CAS: 150145-89-4
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
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Shanghai Macklin Biochemical Co., Ltd
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Product Name: (S)-MCPG Visit Supplier Webpage Request for quotation
CAS: 150145-89-4
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: (+)-Alpha-Methyl-4-Carboxyphenylglycine Visit Supplier Webpage Request for quotation
CAS: 150145-89-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
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View History
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